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noun. an unfortunate happening that hinders or impedes; something that is thwarting or frustrating
A broken toe can be a majorsetbackfor a skater.
A broken toe can be a major setback for a skater.
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What was one setback that R. Mike Mullane encountered before becoming an astronaut?
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disappointment; difficulty; hold-up
achievement; advance
2 syllables
set-back
netback
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