Lyme disease Get Printable Handwriting Hear It! Say It! Write It! Learn It! Spelling Test Definition noun. a bacterial infection spread by ticks that causes fever and rash. Example Sentence Ticks can cause Lyme disease. More Example Sentences Lyme disease can cause serious health problems. Synonyms tick-borne disease; infection; illness Antonyms good health Hear It! Say It! Write It! Lyme disease Switch to cursive Start Share with your friends: